Bi-temporal Image-driven Acute Stroke Evolution Analysis

תקציר מקורי באנגליתarXiv:2602.07535v2 Announce Type: replace-cross Abstract: Acute ischemic stroke requires rapid treatment decisions that are strongly guided by emergency imaging. Admission computed tomography perfusion (CTP) is commonly used to estimate the ischemic core, representing irreversibly damaged tissue, and the penumbra, representing hypoperfused but potentially salvageable tissue. Follow-up diffusion-weighted MRI (DWI) is then used to define the final infarct. Existing imaging approaches primarily focus on core--penumbra segmentation or final-infarct prediction, but provide limited insight into how heterogeneous penumbral tissue evolves after treatment. We propose a bi-temporal tissue phenotyping framework that links admission CTP signatures with follow-up DWI-defined tissue outcome using six ou