Hybrid Machine Learning-Assisted Raman Spectroscopy with Generative Feature Augmentation for Pharmaceutical Identification

תקציר מקורי באנגליתarXiv:2610.02224v1 Announce Type: new Abstract: Rapid and reliable identification of pharmaceutical residues is important for safeguarding public health, ensuring food safety, and enabling practical Raman-based screening. In this study, we propose HyMLRaman, a hybrid Raman spectroscopy framework that combines deep spectral feature extraction, generative models, and classical machine-learning classifiers to identify six pharmaceutical compounds, including amoxicillin, chloramphenicol, ciprofloxacin, tetracycline, ibuprofen, and paracetamol. Raman spectra are converted into spectral images and encoded with several deep neural-network backbones, among which EfficientNet-B3 yields the most effective representation. The resulting 1536-dimensional embeddings are then used to train downstream cla